BDBM449139 US10702498, Compound 13::US11484525, Compound 13

SMILES COc1nc(C)cc(C)c1CNC(=O)NC[C@@H](Cc1ccccc1)[NH+](C)C

InChI Key InChIKey=RZTSQONSLQLOJL-UHFFFAOYSA-O

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 449139   

TargetTumor protein p53-inducible nuclear protein 2(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataEC50:  3.10E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMu-type opioid receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataKi:  550nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMu-type opioid receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataKi:  550nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetKappa-type opioid receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataKi:  1.02E+3nMAssay Description:For a primary screen of selected molecules, binding to OR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). Ea...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMu-type opioid receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM449139(US10702498, Compound 13 | US11484525, Compound 13)
Affinity DataKi:  1.02E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In DepthDetails
US Patent