BDBM448507 US10696638, formula (I) 20::US10696638, formula (I) 21

SMILES NCCN(Cc1ccc(F)cc1)C(=O)Nc1cccc2cnccc12

InChI Key InChIKey=WCUDUDDCPLGWQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448507   

TargetRho-associated protein kinase 1(Human)
Industrial Technology Research Institute

US Patent
LigandPNGBDBM448507(US10696638, formula (I) 21 | US10696638, formula (...)
Affinity DataIC50: 1.00E+3nMAssay Description:ROCK Substrate Coated Plate (Part No 241601): One strip well 96-well plate pre-coated with recombinant MYPT1.Buffer: 25 mM Tris, pH 7.5, 10 mM MgCl2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1(Human)
Industrial Technology Research Institute

US Patent
LigandPNGBDBM448507(US10696638, formula (I) 21 | US10696638, formula (...)
Affinity DataIC50: 1.00E+3nMAssay Description:ROCK Substrate Coated Plate (Part No 241601): One strip well 96-well plate pre-coated with recombinant MYPT1.Buffer: 25 mM Tris, pH 7.5, 10 mM MgCl2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent