BDBM448079 US10689390, Compound 32::US11319326, Compound 32

SMILES CCNC(=O)CC1N=C(c2cc(OC)ccc2-c2cn(C)c(=O)cc12)C(F)(F)F

InChI Key InChIKey=JOWNYTJTMJPZHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448079   

TargetBromodomain-containing protein 4(Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448079(US10689390, Compound 32 | US11319326, Compound 32)
Affinity DataIC50: 49nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448079(US10689390, Compound 32 | US11319326, Compound 32)
Affinity DataIC50: 49nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent