BDBM448072 US10689390, Compound 19::US11319326, Compound 19

SMILES CCOC(=O)CC1N=C(C)c2cc(OC)ccc2-c2cn(C)c(=O)cc12

InChI Key InChIKey=RUGPULSVRRIHCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448072   

TargetBromodomain-containing protein 4(Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448072(US10689390, Compound 19 | US11319326, Compound 19)
Affinity DataIC50: 176nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448072(US10689390, Compound 19 | US11319326, Compound 19)
Affinity DataIC50: 176nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent