BDBM445789 US10669240, Compound 85

SMILES CC(C)Oc1ccc(NC(=O)c2n[nH]c3ccc(cc23)-c2cncc(CN3CC4CC(C3)O4)c2)cn1

InChI Key InChIKey=OLMDVYFVQFYWFE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 445789   

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM445789(US10669240, Compound 85)
Affinity DataIC50: 61nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM445789(US10669240, Compound 85)
Affinity DataEC50:  4nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPulmonary surfactant-associated protein A1(Human)
Samumed

US Patent
LigandPNGBDBM445789(US10669240, Compound 85)
Affinity DataIC50: 180nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 8-point dose-response curves f...More data for this Ligand-Target Pair
In DepthDetails
US Patent