BDBM445536 5-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)methyl]-3-methanesulfonyl-5H-pyrido[3,2-b]indol-7-yl}-4-(2H3)methyl-1-methyl-1H-1,2,3-triazole::US10683290, Example 28

SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(cnc3c2cc1F)S(C)(=O)=O

InChI Key InChIKey=GFEURMROBFWOCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445536   

TargetBromodomain-containing protein 4 [1-477](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445536(US10683290, Example 28 | 5-{8-Fluoro-5-[(S)-(2-flu...)
Affinity DataIC50: 1nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2021
Entry Details
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