BDBM445151 (S)-2-(4-(5-(Trifluoromethyl)-1H-pyrazol-4-yl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine-1-carbonyl)pyrrolidine-1-carbonitrile::US10669234, Example 97::US11319287, Example 97

SMILES FC(F)(F)c1[nH]ncc1-c1nccc2N(CCc12)C(=O)[C@@H]1CCCN1C#N

InChI Key InChIKey=ZTFYENXJVUNCMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445151   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445151(US10669234, Example 97 | (S)-2-(4-(5-(Trifluoromet...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM445151(US10669234, Example 97 | (S)-2-(4-(5-(Trifluoromet...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent