BDBM444989 US10668094, Compound DP

SMILES CCCN1CCC(O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)C(CCC6C5C[C@H](O)[C@]5(C)[C@H](CC[C@]65O)C5=CC(=O)OC5)C4)O[C@H]3C)O[C@H]2C)OC(C)C1

InChI Key InChIKey=NJOZSUQORBIBBP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 444989   

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444989(US10668094, Compound DP)
Affinity DataKi:  9.80nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-2(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444989(US10668094, Compound DP)
Affinity DataKi:  10.5nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444989(US10668094, Compound DP)
Affinity DataKi:  18.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444989(US10668094, Compound DP)
Affinity DataKi:  87.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent