BDBM444981 US10668094, Compound DEcP-(cyclic)

SMILES C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CCC3CC3)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1

InChI Key InChIKey=FTADYJGUJPYFPN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 444981   

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  7.20nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-2(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  12.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  14.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development

US Patent
LigandPNGBDBM444981(US10668094, Compound DEcP-(cyclic))
Affinity DataKi:  86.1nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
In DepthDetails
US Patent