BDBM443331 6'-(5-Fluoro-2-isopropoxyphenyl)-2'- oxo-1',4'-dihydro-2'H- spiro[pyrrolidine-3,3'-quinoline]-1- carbonitrile::US10654853, Example 104::US11236092, Example 104

SMILES CC(C)Oc1ccc(F)cc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key InChIKey=CPSNRECYRWTWFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443331   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443331(US10654853, Example 104 | 6'-(5-Fluoro-2-isopropox...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
Go to US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443331(US10654853, Example 104 | 6'-(5-Fluoro-2-isopropox...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443331(US10654853, Example 104 | 6'-(5-Fluoro-2-isopropox...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent