BDBM443299 (S)-7-(4- Fluorophenyl)- 2-oxo-1,4- dihydro-2H- spiro[pyrido [2,3-b] pyrazine-3,3'- pyrrolidine]-1'- carbonitrile::US10654853, Example 72::US11236092, Example 72

SMILES Fc1ccc(cc1)-c1cnc2N[C@]3(CCN(C3)C#N)C(=O)Nc2c1

InChI Key InChIKey=QVJXHQGNIZZKKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443299   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443299(US10654853, Example 72 | (S)-7-(4- Fluorophenyl)- ...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
Go to US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443299(US10654853, Example 72 | (S)-7-(4- Fluorophenyl)- ...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent