BDBM438775 4-(2-(2-((2,2'-dichloro-3'-(5- (3-hydroxypropyl)-1- methyl-4,5,6,7-tetrahydro- 1H-imidazo[4,5-c]pyridine- 2-carboxamido)-[1,1'- biphenyl]-3-yl)carbamoyl)- 1-methyl-1,4,6,7-tetrahydro- 5H-imidazo[4,5-c]pyridin- 5-yl)ethyl)bicyclo[2.2.l]- heptane-1-carboxylic acid::US10618916, Example 16::US10906920, Example 16::US11414433, Example 16

SMILES Cn1c2CCN(CCCO)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCC45CCC(CC4)(C5)C(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=UOTYKGTYOZLVLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438775   

LigandPNGBDBM438775(4-(2-(2-((2,2'-dichloro-3'-(5- (3-hydroxypropyl)-1...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

LigandPNGBDBM438775(4-(2-(2-((2,2'-dichloro-3'-(5- (3-hydroxypropyl)-1...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438775(4-(2-(2-((2,2'-dichloro-3'-(5- (3-hydroxypropyl)-1...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent