BDBM438764 4-(2-(2-((3'-(5-(1- carbamoylpiperidin-4-yl)-1- methyl-4,5,6,7-tetrahydro- 1H-imidazo[4,5-c]pyridine- 2-carboxamido)-2,2'- dichloro-[1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)ethyl)bicyclo[2.2.1]heptane- 1-carboxylic acid::US10618916, Example 7::US11414433, Example 7

SMILES Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCN(CC2)C(N)=O)c1Cl

InChI Key InChIKey=FGPGZDNMDSVDJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438764   

LigandPNGBDBM438764(4-(2-(2-((3'-(5-(1- carbamoylpiperidin-4-yl)-1- me...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438764(4-(2-(2-((3'-(5-(1- carbamoylpiperidin-4-yl)-1- me...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent