BDBM436474 2-(ethylamino)-9- methyl-6-(3-(4-(2- (methyl(phenethyl) amino)ethyl)-1H-1,2,3- triazol-1-yl)phenyl)- 6,7,8,9-tetrahydro-5H- pyrimido[4,5- e][1,4]diazepin-5-one::US10590140, Example 249

SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-n1cc(CCN(C)CCc3ccccc3)nn1)C2=O

InChI Key InChIKey=PTTMNIDOYABQDY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436474   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103](Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM436474(US10590140, Example 249 | 2-(ethylamino)-9- methyl...)
Affinity DataKi:  300nMAssay Description:α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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