BDBM436189 US10590109, Compound 7

SMILES COCCOc1cc(NC(=O)N(C)c2cccc(C=O)n2)ncc1C#N

InChI Key InChIKey=KIEGFMZLJQWUKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436189   

TargetFibroblast growth factor receptor 4 [460-802](Human)
Nanjing Innocare Pharma Tech

US Patent
LigandPNGBDBM436189(US10590109, Compound 7)
Affinity DataIC50: 10nMAssay Description:FGFR4:The in vitro activity of FGFR4 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1 [308-731](Human)
Nanjing Innocare Pharma Tech

US Patent
LigandPNGBDBM436189(US10590109, Compound 7)
Affinity DataIC50: 1.00E+3nMAssay Description:FGFR1: The in vitro activity of FGFR1 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent