BDBM436039 6-(2-Chloro-6-(trifluoromethoxy)phenyl)-4-methyl-1H-benzo[d]imidazol-2(3H)-one;::US10611730, Example 211

SMILES Cc1cc(cc2[nH]c(=O)[nH]c12)-c1c(Cl)cccc1OC(F)(F)F

InChI Key InChIKey=PNXQSEMPMRJYEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436039   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436039(US10611730, Example 211 | 6-(2-Chloro-6-(trifluoro...)
Affinity DataIC50: 0.100nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent