BDBM435934 5-[2-[(4-Fluorophenyl)ethoxy]-6-methoxy-phenyl]-1,3-dihydrobenzimidazol-2-one;::US10611730, Example 106

SMILES COc1cccc(OCc2ccc(F)cc2)c1-c1ccc2[nH]c(=O)[nH]c2c1

InChI Key InChIKey=UGMSSMQDLBJDSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435934   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435934(US10611730, Example 106 | 5-[2-[(4-Fluorophenyl)et...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent