BDBM435903 5-[2-Methyl-3-[5-(4-pyridyl)-1,2,4-oxadiazol-3-yl]phenyl]-1,3-dihydrobenzimidazol-2-one;::US10611730, Example 75

SMILES Cc1c(cccc1-c1ccc2[nH]c(=O)[nH]c2c1)-c1noc(n1)-c1ccncc1

InChI Key InChIKey=CIWBCZDVSIMYPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435903   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435903(US10611730, Example 75 | 5-[2-Methyl-3-[5-(4-pyrid...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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