BDBM435425 US10570116, Compound C33

SMILES CC(C)(CC(=O)N1CCC(CC1)C(=O)c1ccc(cc1)C(O)=O)Cc1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=LPJHLUNKDITEKL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435425   

TargetPoly [ADP-ribose] polymerase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM435425(US10570116, Compound C33)
Affinity DataIC50: 1.70E+4nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Merck Patent

US Patent
LigandPNGBDBM435425(US10570116, Compound C33)
Affinity DataIC50: 0.510nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Merck Patent

US Patent
LigandPNGBDBM435425(US10570116, Compound C33)
Affinity DataIC50: 0.450nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
Go to US Patent