BDBM434892 (4-([1,1'-biphenyl]-4-yl)-1H- 1,2,3-triazol-1-yl)(2-(pyridin-4- ylmethyl)piperidin-1- yl)methanone::US10583137, Compound 66

SMILES O=C(N1CCCCC1Cc1ccncc1)n1cc(nn1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YNBABVFZKLOVRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434892   

TargetDiacylglycerol lipase-alpha(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM434892(US10583137, Compound 66 | (4-([1,1'-biphenyl]-4-yl...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetDiacylglycerol lipase-beta(Human)
The Scripps Research Institute

US Patent
LigandPNGBDBM434892(US10583137, Compound 66 | (4-([1,1'-biphenyl]-4-yl...)
Affinity DataIC50: 400nMAssay Description:Briefly, membrane proteome (1 mg/ml, 20 μL) was prepared from HEK293T cells (transiently transfected with hDAGLα-FLAG or hDAGLα-S472A-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent