BDBM433566 US10562878, Compound 172 E1::US10562878, Compound 172 E2

SMILES CN(C)CC1(CCCCC1CO)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SBZDQHXDTSOYDS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 433566   

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E2 | US10562878, Compound...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E2 | US10562878, Compound...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E2 | US10562878, Compound...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E2 | US10562878, Compound...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E2 | US10562878, Compound...)
Affinity DataIC50: 127nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E2 | US10562878, Compound...)
Affinity DataIC50: 762nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
US Patent