BDBM432831 5-cyclopropyl-N-((1R,3r,5S)-8-(((1-(3- hydroxypropyl)piperidin-4- yl)methyl)sulfonyl)-8- azabicyclo[3.2.1]octan-3-yl)isoxazole-3- carboxamide::US10577363, Compound 534

SMILES OCCCN1CCC(CS(=O)(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)NC(=O)c2cc(on2)C2CC2)CC1

InChI Key InChIKey=YXDRYSGGDQSHFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432831   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM432831(US10577363, Compound 534 | 5-cyclopropyl-N-((1R,3r...)
Affinity DataIC50: 1.10nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
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US Patent