BDBM43231 (E)-3-(1-benzyl-3-thiophen-2-ylpyrazol-4-yl)prop-2-enoic acid::(E)-3-[1-(phenylmethyl)-3-thiophen-2-yl-4-pyrazolyl]-2-propenoic acid::(E)-3-[1-(phenylmethyl)-3-thiophen-2-yl-pyrazol-4-yl]prop-2-enoic acid::(E)-3-[1-benzyl-3-(2-thienyl)pyrazol-4-yl]acrylic acid::MLS001002570::SMR000369092::cid_2554530

SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1cccs1

InChI Key InChIKey=QPXDCSBPVLLSLU-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43231   

LigandPNGBDBM43231(SMR000369092 | (E)-3-(1-benzyl-3-thiophen-2-ylpyra...)
Affinity DataEC50:  2.18E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetGTPase KRas [1-37](Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43231(SMR000369092 | (E)-3-(1-benzyl-3-thiophen-2-ylpyra...)
Affinity DataEC50:  4.03E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetRas-related protein Rab-2A(Dog)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43231(SMR000369092 | (E)-3-(1-benzyl-3-thiophen-2-ylpyra...)
Affinity DataEC50:  3.64E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM43231(SMR000369092 | (E)-3-(1-benzyl-3-thiophen-2-ylpyra...)
Affinity DataEC50:  1.94E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM43231(SMR000369092 | (E)-3-(1-benzyl-3-thiophen-2-ylpyra...)
Affinity DataEC50:  2.28E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay