BDBM432108 (S)-2-(tert-butoxy)-2-(5-(2-(5,6-dichlorobenzo[d]thiazol-2-yl)- 1,2,3,4-tetrahydroisoquinolin-6-yl)-4-(4,4-dimethylpiperidin-1-yl)- 2,6-dimethylpyridin-3-yl)acetic acid::US10577353, Compound 5

SMILES Cc1nc(C)c(-c2ccc3CN(CCc3c2)c2nc3cc(Cl)c(Cl)cc3s2)c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key InChIKey=GWHMGNAETRNCAC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432108   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432108(US10577353, Compound 5 | (S)-2-(tert-butoxy)-2-(5-...)
Affinity DataEC50:  12nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent