BDBM432080 US10577308, Compound 540

SMILES Cc1cccc(C)c1OCCCNCc1nn(Cc2ccccc2)c2ccccc12

InChI Key InChIKey=ASVAAZZZJNVCIV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 432080   

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432080(US10577308, Compound 540)
Affinity DataIC50: 2.35E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432080(US10577308, Compound 540)
Affinity DataIC50: 2.87E+5nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432080(US10577308, Compound 540)
Affinity DataIC50: 1.20E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432080(US10577308, Compound 540)
Affinity DataIC50: 8.05E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432080(US10577308, Compound 540)
Affinity DataIC50: 1.20E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432080(US10577308, Compound 540)
Affinity DataIC50: 8.05E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent