BDBM432064 US10577308, Compound 531

SMILES Cc1cccc(C)c1OCCCNCc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=SYWJMEMWDFPABO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 432064   

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432064(US10577308, Compound 531)
Affinity DataIC50: 1.25E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432064(US10577308, Compound 531)
Affinity DataIC50: 1.38E+5nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432064(US10577308, Compound 531)
Affinity DataIC50: 1.40E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432064(US10577308, Compound 531)
Affinity DataIC50: 4.09E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 2 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432064(US10577308, Compound 531)
Affinity DataIC50: 1.40E+3nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
The Florey Institute

US Patent
LigandPNGBDBM432064(US10577308, Compound 531)
Affinity DataIC50: 4.09E+4nMAssay Description:Test Protocol for Determining the Potency of Compounds on Nav1.2 and Nav1.6 Subtypes of Voltage-Gated Sodium Ion Channels Expressed in Mammalian Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent