BDBM430032 US10538528, Compound 14

SMILES CC1C(=O)Nc2ncnc(N3CCC(CC3)c3nc(ccc3NCCN3CCCC3)-c3ccoc3)c12

InChI Key InChIKey=PAOJZRPLNNXONF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 430032   

TargetRibosomal protein S6 kinase alpha-1(Human)
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430032(US10538528, Compound 14)
Affinity DataIC50: 0.5nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430032(US10538528, Compound 14)
Affinity DataIC50: 1.70nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430032(US10538528, Compound 14)
Affinity DataIC50: 0.900nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
In DepthDetails
US Patent