BDBM430010 (S)-2-((4-(N-(3-bromo-4- fluorophenyl)-N''- hydroxycarbamimidoyl)-1,2,5- oxadiazol-3-yl)thio)-N-(2- hydroxypropyl)acetamide::US10538497, Example 200::US10538497, Example 203

SMILES C[C@H](O)CNC(=O)CSc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=SSCZGGGSZMNZJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 430010   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430010(US10538497, Example 203 | (S)-2-((4-(N-(3-bromo-4-...)
Affinity DataIC50: 29.9nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430010(US10538497, Example 203 | (S)-2-((4-(N-(3-bromo-4-...)
Affinity DataIC50: 14.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
Go to US Patent