BDBM429890 N-(3-bromo-4-fluorophenyl)-N'- hydroxy-4-({[(2R)-5- oxopyrrolidin-2- yl]methyl}sulfanyl)-1,2,5- oxadiazole-3-carboximidamide::US10538497, Example 83

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1SC[C@H]1CCC(=O)N1

InChI Key InChIKey=SLLXVGYMAFUANL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429890   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429890(US10538497, Example 83 | N-(3-bromo-4-fluorophenyl...)
Affinity DataIC50: 22.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
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Date in BDB:
11/9/2020
Entry Details
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