BDBM42882 (2,5-dimethoxyphenyl)-(5-hydroxy-1-benzofuran-3-yl)methanone::(2,5-dimethoxyphenyl)-(5-hydroxy-3-benzofuranyl)methanone::(2,5-dimethoxyphenyl)-(5-hydroxybenzofuran-3-yl)methanone::(2,5-dimethoxyphenyl)-(5-oxidanyl-1-benzofuran-3-yl)methanone::MLS000105566::SMR000102447::cid_626866

SMILES COc1ccc(OC)c(c1)C(=O)c1coc2ccc(O)cc12

InChI Key InChIKey=ZZXSSXYHBWCWGF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 42882   

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM42882(cid_626866 | (2,5-dimethoxyphenyl)-(5-hydroxy-1-be...)
Affinity DataIC50: 9.31E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM42882(cid_626866 | (2,5-dimethoxyphenyl)-(5-hydroxy-1-be...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM42882(cid_626866 | (2,5-dimethoxyphenyl)-(5-hydroxy-1-be...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged SIRT1 coding region (156-664) (unknown origin) expressed in Escherichia coli BL21(DE3) using 31.25 uM ac-RHKKac-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed