BDBM427071 US10544132, Example 25::US10981898, Example 25::US11236047, Example 25::US20230338337, Example 25
SMILES CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(cc1)C#N)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
InChI Key InChIKey=KUYDFZZMIJDWQY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 427071
Affinity DataIC50: 7.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataIC50: 7.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Each assay was performed in a final volume of 15 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair