BDBM4261 (2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-[(4-hydroxyphenyl)formamido]-4-phenylbutanoyl]pyrrolidine-2-carboxamide::4-Hydroxybenzoyl-(2S,3S)-AHPBA-4(S)-Cl-Pro-NH-t-Bu::AHPBA 30::CHEMBL324732

SMILES CC(C)(C)NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc(O)cc1

InChI Key InChIKey=XZILXXASVMAMCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4261   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4261(4-Hydroxybenzoyl-(2S,3S)-AHPBA-4(S)-Cl-Pro-NH-t-Bu...)
Affinity DataIC50: 33nMAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4261(4-Hydroxybenzoyl-(2S,3S)-AHPBA-4(S)-Cl-Pro-NH-t-Bu...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed