BDBM4254 (2S,4S)-N-tert-butyl-4-chloro-1-[(2S,3S)-2-hydroxy-3-[(2-iodophenyl)formamido]-4-phenylbutanoyl]pyrrolidine-2-carboxamide::2-Iodobenzoyl-(2S,3S) -AHPBA-4(S) -Cl-Pro-NH- t-Bu::AHPBA 23::CHEMBL333833

SMILES CC(C)(C)NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1I

InChI Key InChIKey=MVJZVBCJARROQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4254   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4254(CHEMBL333833 | 2-Iodobenzoyl-(2S,3S) -AHPBA-4(S) -...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM4254(CHEMBL333833 | 2-Iodobenzoyl-(2S,3S) -AHPBA-4(S) -...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed