BDBM423501 US10508115, Compound Ic-03

SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4cccc(CNC5COC5)n4)cc3)c2n1

InChI Key InChIKey=HMIZZDSEMNUTOP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423501   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423501(US10508115, Compound Ic-03)
Affinity DataEC50:  4.27nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423501(US10508115, Compound Ic-03)
Affinity DataEC50:  78nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...More data for this Ligand-Target Pair
In DepthDetails
US Patent