BDBM423495 US10508115, Compound Ib-14

SMILES CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNCCS(C)(=O)=O)cc4)nc3)c2n1

InChI Key InChIKey=OMGCSPOURRFJGB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423495   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423495(US10508115, Compound Ib-14)
Affinity DataEC50:  1.80nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423495(US10508115, Compound Ib-14)
Affinity DataEC50:  18.9nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...More data for this Ligand-Target Pair
In DepthDetails
US Patent