BDBM423421 WO2005113580-Ex-17

SMILES COCC(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)(C)C)NC(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=IULLQBINVRGFGJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 423421   

TargetReplicase polyprotein 1ab(SARS-CoV)
Pfizer

WIPO
LigandPNGBDBM423421(WO2005113580-Ex-17)
Affinity DataIC50: 105nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
In DepthDetails
WIPO WO2005113580

TargetReplicase polyprotein 1ab(SARS-CoV)
Pfizer

WIPO
LigandPNGBDBM423421(WO2005113580-Ex-17)
Affinity DataEC50:  4.60E+4nMAssay Description:Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...More data for this Ligand-Target Pair
In DepthDetails
WIPO WO2005113580