BDBM42323 1-(10H-phenothiazin-2-yl)ethanone::MLS000047624::SMR000033635::cid_81131

SMILES CC(=O)c1ccc2Sc3ccccc3Nc2c1

InChI Key InChIKey=JWGBOHJGWOPYCL-UHFFFAOYSA-N

Data  8 KI  9 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 42323   

TargetNADPH oxidase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 156nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoKEGG
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Date in BDB:
7/11/2011
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TargetNADPH oxidase 4(Human)
TBA

Curated by ChEMBL

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NOX4 transfected in HEK293T cells incubated for 16 hrs ans measured after 30 mins by luminol-chemiluminescence based assayMore data for this Ligand-Target Pair

Target InfoKEGG
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Date in BDB:
12/19/2024
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TargetNADPH oxidase 3(Human)
TBA

Curated by ChEMBL

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NOX3 transfected in HEK293T cells incubated for 16 hrs ans measured after 30 mins by luminol-chemiluminescence based assayMore data for this Ligand-Target Pair

Target InfoKEGG
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Date in BDB:
12/19/2024
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TargetCytochrome b-245 heavy chain(Human)
TBA

Curated by ChEMBL

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NOX2 transfected in HEK293T cells incubated for 16 hrs ans measured after 30 mins by luminol-chemiluminescence based assayMore data for this Ligand-Target Pair

Target InfoPDB
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Date in BDB:
12/19/2024
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TargetNADPH oxidase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 250nMAssay Description:Inhibition of human NOX1 transfected in HEK293T cells incubated for 16 hrs and measured after 30 mins by luminol-chemiluminescence based assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
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Date in BDB:
12/19/2024
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TargetCytochrome b-245 heavy chain(Human)
TBA

Curated by ChEMBL

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

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Date in BDB:
7/31/2011
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TargetNADPH oxidase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoKEGG
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Date in BDB:
7/30/2011
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TargetNADPH oxidase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 129nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoKEGG
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Date in BDB:
7/12/2011
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TargetNADPH oxidase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataIC50: 250nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoKEGG
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Date in BDB:
7/30/2011
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TargetLysosomal acid glucosylceramidase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataEC50: >5.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
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Date in BDB:
5/20/2011
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Target5-hydroxytryptamine receptor 2B(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi:  300nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
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Date in BDB:
8/3/2011
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TargetAlpha-2A adrenergic receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

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Date in BDB:
8/3/2011
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TargetAlpha-2B adrenergic receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

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Date in BDB:
8/3/2011
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TargetAlpha-2C adrenergic receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDB
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Date in BDB:
8/3/2011
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TargetD(3) dopamine receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDB
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Date in BDB:
8/3/2011
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TargetKappa-type opioid receptor [1-7](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
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Date in BDB:
8/3/2011
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TargetMuscarinic acetylcholine receptor M1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

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Date in BDB:
8/3/2011
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TargetMuscarinic acetylcholine receptor M2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(SMR000033635 | MLS000047624 | cid_81131 | 1-(10H-p...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

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Date in BDB:
8/3/2011
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