BDBM421529 US10508086, Example 119::US10995073, Example 119

SMILES Cc1nnc(s1)-n1cnc2ccc(cc12)S(=O)(=O)NC1(C)CC1

InChI Key InChIKey=ALHIKLRFEXYUCD-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 421529   

TargetPoly(ADP-ribose) glycohydrolase(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM421529(US10508086, Example 119 | US10995073, Example 119)
Affinity DataEC50:  1.03E+3nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetADP-ribosylhydrolase ARH3(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM421529(US10508086, Example 119 | US10995073, Example 119)
Affinity DataIC50: 1.50E+5nMAssay Description:ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM421529(US10508086, Example 119 | US10995073, Example 119)
Affinity DataIC50: 1.50E+5nMAssay Description:PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly(ADP-ribose) glycohydrolase(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM421529(US10508086, Example 119 | US10995073, Example 119)
Affinity DataEC50:  1.03E+3nMAssay Description:PARG In vitro assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length PARG (Produced internally by ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetADP-ribosylhydrolase ARH3(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM421529(US10508086, Example 119 | US10995073, Example 119)
Affinity DataIC50: 1.50E+5nMAssay Description:ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM421529(US10508086, Example 119 | US10995073, Example 119)
Affinity DataIC50: 1.50E+5nMAssay Description:PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...More data for this Ligand-Target Pair
In DepthDetails
US Patent