BDBM419916 US10464947, Example 18

SMILES Cc1noc(C)c1-c1ccc2[nH]c(=O)n3C(COc1c23)C1CCCO1

InChI Key InChIKey=XIRBQZLMMWMKGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419916   

TargetBromodomain-containing protein 4 [42-168](Human)
Incyte Holdings

US Patent
LigandPNGBDBM419916(US10464947, Example 18)
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
Incyte Holdings

US Patent
LigandPNGBDBM419916(US10464947, Example 18)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2020
Entry Details
Go to US Patent