BDBM418841 3-methyl-4-({4-[({2- [methyl(methylsulfonyl)amino]pyridin-3- yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (341)::US10450297, Example 341::US10450297, Example 342

SMILES CN(c1ncccc1CNc1nc(Nc2ccc(cc2C)C(N)=O)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=DTDASEBYOMICIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 418841   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418841(US10450297, Example 341 | 3-methyl-4-({4-[({2- [me...)
Affinity DataIC50: 0.595nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
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TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418841(US10450297, Example 341 | 3-methyl-4-({4-[({2- [me...)
Affinity DataIC50: 1.03nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent