BDBM417112 1-((3R,5S)-1-acryloyl-5-methylpyrrolidin-3-yl)-4-amino-N-(4-(2-dimethylamino)-2-oxoethyl)-2,3-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3-carboxamide::US10329300, Example 79

SMILES C[C@H]1CN(C[C@@H]1n1nc(C(=O)Nc2ccc(CC(=O)N(C)C)c(C)c2C)c2c(N)ncnc12)C(=O)C=C

InChI Key InChIKey=YEEJNCDOAQYNAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 417112   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM417112(1-((3R,5S)-1-acryloyl-5-methylpyrrolidin-3-yl)-4-a...)
Affinity DataIC50: 17nMAssay Description:For setting the conditions for the method for measuring the in vitro inhibitory activity of a compound against HER2-phosphorylating activity, Profile...More data for this Ligand-Target Pair
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Date in BDB:
8/24/2020
Entry Details
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