BDBM415453 3-Ethyl-5-methyl-6-[(5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)methyl]-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione::US10428083, Example 116

SMILES CCn1c(=O)n(CCC(F)(F)F)c2sc(Cn3cn[nH]c3=O)c(C)c2c1=O

InChI Key InChIKey=GTNNKMDPAIQNRD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 415453   

TargetAdenosine receptor A2b(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(US10428083, Example 116 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  12nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
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TargetAdenosine receptor A3(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(US10428083, Example 116 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  330nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(US10428083, Example 116 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  790nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415453(US10428083, Example 116 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  3.30E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent