BDBM415452 3-Ethyl-5-methyl-6-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)methyl]-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione::US10428083, Example 113

SMILES CCn1c(=O)n(CCC(F)(F)F)c2sc(Cn3nc[nH]c3=O)c(C)c2c1=O

InChI Key InChIKey=HXOPQSRXIGIZDD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 415452   

TargetAdenosine receptor A2b(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415452(US10428083, Example 113 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  6.40nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
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TargetAdenosine receptor A1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415452(US10428083, Example 113 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  1.50E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415452(US10428083, Example 113 | 3-Ethyl-5-methyl-6-[(5-o...)
Affinity DataKi:  1.70E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent