BDBM415450 3-Isopropyl-1-(2-methoxyethyl)-5-methyl-6-[(2-oxoimidazolidin-1-yl)methyl]thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione::US10428083, Example 86

SMILES COCCn1c2sc(CN3CCNC3=O)c(C)c2c(=O)n(C(C)C)c1=O

InChI Key InChIKey=MQDFKQJWAVLPSG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 415450   

TargetAdenosine receptor A2b(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(US10428083, Example 86 | 3-Isopropyl-1-(2-methoxye...)
Affinity DataKi:  2.70nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
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TargetAdenosine receptor A2a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(US10428083, Example 86 | 3-Isopropyl-1-(2-methoxye...)
Affinity DataKi:  270nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(US10428083, Example 86 | 3-Isopropyl-1-(2-methoxye...)
Affinity DataKi:  1.10E+3nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetAdenosine receptor A3(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM415450(US10428083, Example 86 | 3-Isopropyl-1-(2-methoxye...)
Affinity DataKi:  1.60E+5nMAssay Description:The binding properties of the test compounds on adenosine receptors were determined in binding studies with radioligands. For this purpose, membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent