BDBM41535 US8575145, 106::US8575145, 66

SMILES FC1(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CCNCC1

InChI Key InChIKey=XQTDEFZROIJVJH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 41535   

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM41535(US8575145, 66 | US8575145, 106)
Affinity DataIC50: 0.5nMAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM41535(US8575145, 66 | US8575145, 106)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM41535(US8575145, 66 | US8575145, 106)
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM41535(US8575145, 66 | US8575145, 106)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent