BDBM414885 US10428028, Coding A1

SMILES Nc1ccccc1NC(=O)c1ccc2n(Cc3cccnc3)ncc2c1

InChI Key InChIKey=VQWRDIFVQPSZFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 414885   

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM414885(US10428028, Coding A1)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM414885(US10428028, Coding A1)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM414885(US10428028, Coding A1)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
Go to US Patent