BDBM414880 N-Ethyl-2-fluoro-4-methyl-N-[1-((R)-3,3,3-trifluoro-2-hydroxy-2-methyl-propionyl)-piperidin-4-yl]-benzamide::US10428024, Compound A64

SMILES CCN(C1CCN(CC1)C(=O)[C@@](C)(O)C(F)(F)F)C(=O)c1ccc(C)cc1F

InChI Key InChIKey=HWWWBDKMWZWYMJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414880   

LigandPNGBDBM414880(N-Ethyl-2-fluoro-4-methyl-N-[1-((R)-3,3,3-trifluor...)
Affinity DataIC50: 410nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM414880(N-Ethyl-2-fluoro-4-methyl-N-[1-((R)-3,3,3-trifluor...)
Affinity DataKd:  69nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
In DepthDetails
US Patent