BDBM414839 (3S,4S) N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperidine-4-carboxamide::US10428024, Compound A10

SMILES C[C@@H]1CN(CC[C@@H]1C(=O)N(C)c1ccc(Cl)cc1)C(=O)[C@@](C)(O)C(F)(F)F

InChI Key InChIKey=JFKCOZFUPKSNIN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414839   

LigandPNGBDBM414839((3S,4S) N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,...)
Affinity DataIC50: 110nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM414839((3S,4S) N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,...)
Affinity DataKd:  26nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
In DepthDetails
US Patent