BDBM414095 (R)-1-(7-methyl-6-(1H- pyrrolo[2,3-b]pyridin-4- yl)-5,6,7,8-tetrahydro- pyrido[4,3-d]pyrimidin-4- yl)azetidine-3-carbonitrile::US10421765, Example 81::US10745420, Example 81

SMILES C[C@@H]1Cc2ncnc(N3CC(C3)C#N)c2CN1c1ccnc2[nH]ccc12

InChI Key InChIKey=KDUONAOPKWXAEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414095   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414095(US10421765, Example 81 | (R)-1-(7-methyl-6-(1H- py...)
Affinity DataIC50: 246nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414095(US10421765, Example 81 | (R)-1-(7-methyl-6-(1H- py...)
Affinity DataIC50: 246nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent