BDBM414077 Methyl (S)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3- b]pyridin-4-yl)-7-methyl- 5,6,7,8-tetrahydropyrido- [4,3-d]pyrimidin-4-yl)- piperidine-3-carboxylate::US10421765, Example 63::US10745420, Example 63

SMILES COC(=O)[C@H]1CCCN(C1)c1ncnc2C[C@@H](C)N(Cc12)c1cc(Cl)nc2[nH]ccc12

InChI Key InChIKey=PRYXSNIFSXSZSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414077   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414077(US10421765, Example 63 | Methyl (S)-1-((R)-6-(6- c...)
Affinity DataIC50: 86nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2020
Entry Details
Go to US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM414077(US10421765, Example 63 | Methyl (S)-1-((R)-6-(6- c...)
Affinity DataIC50: 86nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent